2017 Fall Symposium & Business Meeting

  • 08 Nov 2017
  • 12:30 PM
  • 09 Nov 2017
  • 9:00 PM
  • University of Massachusetts, Amherst

Registration

  • Registration for Fall Symposium Speakers Only

Register


Join NESM for our annual Fall Symposium & Business Meeting on Thursday, November 8th and 9th at the University of Massachusetts, Amherst, MA! 


The meeting will consist of four or five technical talks, a poster session, a coffee break, a catered lunch, and a business meeting in which elections will be held for several positions on the Board of Directors. Election ballots will be distributed with the Fall E-Newsletter.


We will be celebrating the 50th Anniversary of our Society!


Nov 8th:  Workshops at the new Light Microscopy Facility.

This facility is one of a few designated Nikon Centers of Excellence.  Nikon specialists will be providing a unique opportunity for training and demonstrations of the diverse available microscope.

You can even bring your own samples to test!!!


Register for workshops HERE.

12-1pm: Check-in
1-3pm: Workshop 1 (Super-resolution) and Workshop 2 (High Content Imaging)
3-5pm: Workshop 3 (Enhanced resolution) and Workshop 4 (Scripting/JOBS)


Nov 9thSymposium

9am  Registration/45 min tour of EM facility

10am  Welcome

10:10-10:50am  Talk 1 Tamomi Tani

10:50-11:30am Talk 2 Dan Needleman

11:30-12:30pm  Poster Session

12:30-2pm  NESM History/Lunch/Business Meeting

2-2:40pm  Talk 3 Bruce Goode

2:40-3:20pm  Talk 4 Jennifer Ross

3:30-4pm  Closing Celebration


Talk 1: Tamomi Tani


Abstract 1:


Bio 1:



Talk 2: Dan Needleman; Biophysics of Spindle Positioning and Elongation


Abstract 2:  The spindle is positioned asymmetrically during the first mitotic

division in C. elegans.  We are investigating how different forces

coordinated to move the spindle, and if these forces are generated from

interactions with the cytoplasm, the cortex, or a combination of both.

For this purpose, we constructed a laser ablation system capable of

cutting complex patterns with high spatial and temporal precision, and

we are applying it to quantitatively perturb spindle movements.  We are

also using fluorescent nanodiamonds to track cytoplasmic fluid flow as

the spindle moves. We interpret our data using a combination of theory

and simulations (in collaboration with Mike Shelley,

NYU/Courant/Flatiron). Our results argue that pulling forces from the

cortex drive key aspects of spindle motions, including the initial

centering, subsequent asymmetric positioning, transverse oscillating

behaviors, and elongation.  We hope to provide a quantitative,

integrated understanding of spindle positioning.



Talk 3: Bruce Goode


Abstract 3:


Bio 3:



Talk 4: Jennifer Ross; How does the cell organize its insides?


Abstract 4:  The cell is a complex autonomous machine taking in information, performing computations, and responding to the environment. To enable agile read/write capabilities, much of the molecular biochemistry that performs these computations must be transient and weak, allowing signals to be carried as a function of the concentration of numerous and coupled interactions. Traditionally, biochemical experiments can only measure strongly interacting systems that can last for long times in dilute concentrations. We have developed microscopy measurements to enable to visualization of weak, transient interactions and the resulting emergent behaviors of coupled systems. I will present excerpts from stories where many weak, transient interactions can have strong repercussions on the overall activity and can, in fact, overpower strongly interacting systems. These studies involve the microtubule cytoskeleton and the transport motor, kinesin-1.  Our results reveal a fundamentally important aspect of cellular self-organization: weak, transient interacting species can tune their interaction strength directly by tuning the local concentration to act like a rheostat. The tunability of weak, transient interactions is a fundamental activity of biological systems, and our insights will ultimately enable us to learn how to engineer thesis systems to create biological or biomimetic devices.



Bio 4:  Ross is the director of the new Massachusetts Center for Autonomous Materials (MassCAM) and an award-winning biophysicist studying the organization of the microtubule cytoskeleton and microtubule-based enzymes using high-resolution single molecule imaging techniques. She has a degree in Physics, and has studied the microtubule cytoskeleton for over a decade. As a Cottrell Scholar, Ross has pioneered innovative teaching techniques that are being adopted around the world. Specifically, ahe has taught at several international short courses on microscopy including Analytical and Quantitative Microscopy (AQLM) at the Marine Biology Laboratory and the Bangalore Microscopy Course at the National Centre for Biological Science in Bangalore, India. She has also served as the President of NESM in the past. She is also an advocate for women and under-represented groups and has a blog to help others make it in academics.



Location

UMass, Amherst

Life Science Laboratories

240 Thatcher Way

Amherst, MA  01003


Parking

Campus center garage (pay per hour)



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