Events

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Upcoming events

    • 08 Nov 2017
    • 12:30 PM
    • 09 Nov 2017
    • 9:00 PM
    • University of Massachusetts, Amherst
    Register


    Join NESM for our annual Fall Symposium & Business Meeting on Thursday, November 8th and 9th at the University of Massachusetts, Amherst, MA! 


    The meeting will consist of four or five technical talks, a poster session, a coffee break, a catered lunch, and a business meeting in which elections will be held for several positions on the Board of Directors. Election ballots will be distributed with the Fall E-Newsletter.


    We will be celebrating the 50th Anniversary of our Society!


    Nov 8th:  Workshops at the new Light Microscopy Facility.

    This facility is one of a few designated Nikon Centers of Excellence.  Nikon specialists will be providing a unique opportunity for training and demonstrations of the diverse available microscope.

    You can even bring your own samples to test!!!


    Register for workshops HERE.

    12-1pm: Check-in
    1-3pm: Workshop 1 (Super-resolution) and Workshop 2 (High Content Imaging)
    3-5pm: Workshop 3 (Enhanced resolution) and Workshop 4 (Scripting/JOBS)


    Nov 9thSymposium

    9am  Registration/45 min tour of EM facility

    10am  Welcome

    10:10-10:50am  Talk 1 Tamomi Tani

    10:50-11:30am Talk 2 Dan Needleman

    11:30-12:30pm  Poster Session

    12:30-2pm  NESM History/Lunch/Business Meeting

    2-2:40pm  Talk 3 Bruce Goode

    2:40-3:20pm  Talk 4 Jennifer Ross

    3:30-4pm  Closing Celebration


    Talk 1: Tamomi Tani


    Abstract 1:


    Bio 1:



    Talk 2: Dan Needleman; Biophysics of Spindle Positioning and Elongation


    Abstract 2:  The spindle is positioned asymmetrically during the first mitotic

    division in C. elegans.  We are investigating how different forces

    coordinated to move the spindle, and if these forces are generated from

    interactions with the cytoplasm, the cortex, or a combination of both.

    For this purpose, we constructed a laser ablation system capable of

    cutting complex patterns with high spatial and temporal precision, and

    we are applying it to quantitatively perturb spindle movements.  We are

    also using fluorescent nanodiamonds to track cytoplasmic fluid flow as

    the spindle moves. We interpret our data using a combination of theory

    and simulations (in collaboration with Mike Shelley,

    NYU/Courant/Flatiron). Our results argue that pulling forces from the

    cortex drive key aspects of spindle motions, including the initial

    centering, subsequent asymmetric positioning, transverse oscillating

    behaviors, and elongation.  We hope to provide a quantitative,

    integrated understanding of spindle positioning.



    Talk 3: Bruce Goode


    Abstract 3:


    Bio 3:



    Talk 4: Jennifer Ross; How does the cell organize its insides?


    Abstract 4:  The cell is a complex autonomous machine taking in information, performing computations, and responding to the environment. To enable agile read/write capabilities, much of the molecular biochemistry that performs these computations must be transient and weak, allowing signals to be carried as a function of the concentration of numerous and coupled interactions. Traditionally, biochemical experiments can only measure strongly interacting systems that can last for long times in dilute concentrations. We have developed microscopy measurements to enable to visualization of weak, transient interactions and the resulting emergent behaviors of coupled systems. I will present excerpts from stories where many weak, transient interactions can have strong repercussions on the overall activity and can, in fact, overpower strongly interacting systems. These studies involve the microtubule cytoskeleton and the transport motor, kinesin-1.  Our results reveal a fundamentally important aspect of cellular self-organization: weak, transient interacting species can tune their interaction strength directly by tuning the local concentration to act like a rheostat. The tunability of weak, transient interactions is a fundamental activity of biological systems, and our insights will ultimately enable us to learn how to engineer thesis systems to create biological or biomimetic devices.



    Bio 4:  Ross is the director of the new Massachusetts Center for Autonomous Materials (MassCAM) and an award-winning biophysicist studying the organization of the microtubule cytoskeleton and microtubule-based enzymes using high-resolution single molecule imaging techniques. She has a degree in Physics, and has studied the microtubule cytoskeleton for over a decade. As a Cottrell Scholar, Ross has pioneered innovative teaching techniques that are being adopted around the world. Specifically, ahe has taught at several international short courses on microscopy including Analytical and Quantitative Microscopy (AQLM) at the Marine Biology Laboratory and the Bangalore Microscopy Course at the National Centre for Biological Science in Bangalore, India. She has also served as the President of NESM in the past. She is also an advocate for women and under-represented groups and has a blog to help others make it in academics.



    Location

    UMass, Amherst

    Life Science Laboratories

    240 Thatcher Way

    Amherst, MA  01003


    Parking

    Campus center garage (pay per hour)



    • 08 Nov 2017
    • 2 sessions
    • UMass, Amherst, MA
    • 4
    Register

    Workshops at the new Light Microscopy Facility.


    This facility is one of a few designated Nikon Centers of Excellence.  Nikon specialists will be providing a unique opportunity for training and demonstrations of the diverse available microscope.


    You can even bring your own samples to test!!!  (please email LMF@umass.edu to arrange this)



    12-1pm: Registration
    1-3pm: Workshop 1 (Super-resolution) and Workshop 2 (High Content Imaging)
    3-5pm: Workshop 3 (Enhanced resolution) and Workshop 4 (Scripting/JOBS)


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